“They’re Made Out of Meat”, by Terry Bisson, is a 1991 science fiction story about first contact with a truly alien civilization. If you haven’t read it already, then check it out here. It’ll take just two or three minutes.
Because it’s limited to a dialogue between two characters, “They’re Made Out of Meat” has gotten numerous film and audio adaptations (like this Studio 360 version). This post compiles every single film adaptation, from “the film student one” to “the one that’s in Russian” to “the one that hurts your ears and should not be listened to.” If you know of any others, please let me know so that I can add them.